Classification & Staging
Once active multiple myeloma has been diagnosed, doctors will want to determine the extent – or stage – of the disease.
Knowing the stage of the myeloma helps doctors understand how serious the disease is, establish a customized treatment plan, and arrive at a prognosis (an estimate of how the disease will progress).
Several systems are used to stage active myeloma. The two main systems are the International Staging System (ISS) and the Durie Salmon Staging System.
|International Staging System (ISS)||Durie Salmon Staging System|
Based upon two blood test results:
Requires a number of other blood tests, including:
In both systems, active myeloma is staged according to its extent at the time of diagnosis. There are three possible stages, referred to as Stage I, Stage II and Stage III, in order of increasing disease severity.
For more information, downlaod the Multiple Myeloma Patient Handbook
Designed to provide educational support to patients, caregivers, families, and friends, this handbook gives accurate, reliable, and clear information on myeloma. Topics cover its causes and effects, how it is diagnosed, and the treatment options available in Canada.
Download it now.